Protein microarrays have important applications for the analysis of substrate-enzyme, DNA-protein, RNA-protein, protein-protein, and ligand-protein interactions. However, proteins are composed of twenty different amino acids, which result in the production of diverse molecules with highly different properties. Proteins may be hydrophilic or hydrophobic, acidic or basic, and may acquire many different covalent chemical modifications, such as phosphorylation and glycosylation. PCC's technology corresponds to the diversity of such protein structure simultaneously with the necessity of maintaining all the functionality of each protein, and proposes the significant problem that must overcome to develop a broadly useful protein microarray technology.


 

Protein Chip

Protein  beads were mounted on the glass slide.